From Athens:
Track 1: 275 km
Athens – Corinth – Nafpaktos – High Country (via Rion-Antirrion).
Track 2: 345 km
Athens – Livadia-Distomo-Desfina Itea – Nafpaktos – Upper Country
Route 3: 290 km
Athens – Livadia – Amphissa-Delphi – Lake Mornou-Upper Country

Note: If you choose to route 3 after Amphissa, go to Lidoriki and 5 km turn left before you reach the lake Mornou you open your front

From Thessaloniki:
Track 1: 513 km
Thessaloniki – Lamia – Bralos (exit immediately after Lamia right) Amphissa Itea – Nafpaktos – Upper country.
Track 2: 480 km
Thessaloniki – Lamia – Bralos (exit immediately after Lamia right) – Amphissa (through Amphissa) – Lake Mornou (Yperochi!!) – Upper Country. This route is beautiful and kilometer shorter
Route 3: 640chlm
Thessaloniki – Ioannina (from Egnantia) – Andírrion – Upper Country

Regarding accessibility to the area for the winter months, do not worry:
The road is paved in good condition and never closes!

(Always carry chains with you in the winter months)

Distances:
1) Athens – Nafpaktos: 220 km
2) Thessaloniki – Nafpaktos: 458 km
3) Nafpaktos – Upper Country: 50 km
4) Patras – Upper Country: 70 km
5) Agrinio-Upper Country: 135 km
6) Upper-Ioannina Country: 300 km

Useful telephone numbers:
Lepanto Police Department: 0030 26340-27258
High Country Health Center: 0030 26340 41444, 26340 41209
Health Center Nafpaktos 0030 26340 23690-1
Municipal District Apodotia (Upper Country): 0030 26340 41690
Bus Nafpaktos 0030 26340 27224